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【健康报道】研究:维生素补充剂可能会损害乳腺癌的治疗 Study: Vitamin Supplements May Harm Breast Cancer Treatment

来源:慢速英语   时间:2020-01-13 11:16:17

A new study suggests that patients with breast cancer who take additional vitamins during chemotherapy treatment may face increased risks.


一项新的研究表明,在化疗期间服用额外维生素的乳腺癌患者可能面临更大的风险。


Researchers said the use of dietary supplements that increase levels of antioxidants, iron, vitamin B12 and omega-3 fatty acids appeared to lower the effectiveness of chemotherapy. Researchers reported their findings in the Journal of Clinical Oncology.


研究人员说,使用膳食补充剂会增加抗氧化剂,铁,维生素B12和omega-3脂肪酸的含量,似乎会降低化疗的效果。研究人员在《临床肿瘤学杂志》上报告了他们的发现。


Christine Ambrosone is the head of cancer prevention and control at the Roswell Park Comprehensive Cancer Center in Buffalo, New York. She said, "From this study and others in the literature, it seems that it may not be wise to take supplements during chemotherapy."


克里斯汀·安布罗松(Christine Ambrosone)是纽约布法罗罗斯威尔公园综合癌症中心癌症预防和控制的负责人。她说:“根据这项研究以及其他文献,在化疗期间服用补品似乎并不明智。”


"It's thought that antioxidants might interfere with the ability of chemotherapy to kill cancer cells," Ambrosone said.


安布罗松说:“人们认为抗氧化剂可能会干扰化学疗法杀死癌细胞的能力。”


Some doctors have been advising patients for a number of years not to take antioxidants during chemotherapy. "But there was no strong empirical data for that recommendation," Ambrosone said.


多年来,一些医生一直建议患者在化疗期间不要服用抗氧化剂。安布罗松说:“但是,对于该建议,没有强有力的经验数据。”


So, Ambrosone and other researchers decided to study whether supplement use might affect chemotherapy's effectiveness. They looked for evidence in an earlier study on diet, exercise, lifestyle and cancer results.


因此,安布罗松和其他研究人员决定研究补充剂的使用是否会影响化学疗法的有效性。他们在较早的饮食,运动,生活方式和癌症结果研究中寻找证据。

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In the earlier research, people who took part were asked about their use of supplements at the beginning of and during treatment, and about their lifestyle, diet and exercise.


在较早的研究中,与会人员被问及在治疗开始时和治疗过程中使用补充剂的情况,生活方式,饮食和运动情况。


The researchers studied 1,134 patients who filled out the surveys and followed them for a median of six years. Their supplement use was much lower than usual, Ambrosone said. About 20 percent of patients were taking supplements before starting chemotherapy and 13 percent during the treatments.


研究人员研究了1,134名患者,这些患者填写了调查表,并对其进行了平均6年的随访。 Ambrosone说,他们的补充使用比平常低得多。大约20%的患者在开始化疗之前服用补充剂,而在治疗期间则服用13%。


The researchers searched for other possibilities that might increase the risk of the disease reappearing or of death. They found that patients who took any supplements at the beginning of and during chemotherapy were 41 percent more likely to have their breast cancer return than those who did not. In addition, the supplement takers were 40 percent more likely to die later on compared to patients using no supplements. The supplements included vitamin A, C and E.


研究人员寻找其他可能增加疾病复发或死亡风险的可能性。他们发现,在化疗开始和化疗期间服用任何补品的患者比未服用补品的患者患乳腺癌的可能性高41%。此外,与不使用补充剂的患者相比,接受补充剂的人死亡的可能性高出40%。补充剂包括维生素A,C和E。


Vitamin B12 and iron


维生素B12和铁


Those taking vitamin B12 and iron supplements were at greater risk of cancer returning, the researchers said. Women taking vitamin B12 were 83 percent more likely to experience a return of their disease and 22 percent more likely to die from it than those not taking those supplements. Those taking omega-3 supplements were 67 percent more likely to have the disease return. That percentage rose to 79 for those taking iron supplements.


研究人员说,那些服用维生素B12和铁补充剂的人罹患癌症的风险更大。与未服用维生素B12的妇女相比,服用维生素B12的妇女患病的可能性高83%,死于这种疾病的可能性高22%。那些服用omega-3补充剂的人患病的可能性增加67%。服用铁补充剂的人的这一比例上升到79。


Amy Tiersten is a professor of medicine at the Icahn School of Medicine at Mount Sinai in New York City. She said she was pleased with the research.


艾米·提尔斯滕(Amy Tiersten)是纽约市西奈山(Icahn)伊坎医学院的医学教授。她说她对这项研究感到满意。


"For years we have been cautioning patients about the use of vitamins, in particular antioxidants, during chemotherapy for breast cancer," Tiersten said.


蒂尔斯滕说:“多年来,我们一直在提醒患者在乳腺癌化疗期间使用维生素,特别是抗氧化剂。”


In an email to Reuters news service, she said that she "always told patients on chemotherapy that the best way to get their vitamins is through a well-balanced diet, and will continue to do so given these data."


在给路透社新闻服务的一封电子邮件中,她说:“她总是告诉接受化学疗法的患者,摄取维生素的最佳方法是通过均衡饮食,并且在获得这些数据的情况下将继续这样做。”


重点词汇:

Words in This Story:

supplement –n. an additional amount of something (like vitamins or minerals)

literature –n. books and articles about a particular subject

empirical –adj. based on testing or experience

recommendation –n. a suggestion for someone to do something

habit –n. a usual way of behaving, something done in a repeated way

survey –n. an activity in which people are asked questions in order to gather information about what most people do or think

median –adj. the middle value in a series of numbers

recurrence –n. when something happens again or returns

caution –v. to warn or tell (someone) about a possible danger, problem, etc.


链接:

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