Scientists are developing a medical devicethat could tell them more about the human body, and help them develop more-effective treatments for cancer, heart disease and brain disorders.
It would be the world’s first full-body PET scanner. PET stands for Positron Emission Tomography. PET scanners create 3-D images of what is happening in the body.
Researchers are calling the large scanner that they are developing Explorer. It will give medical workers images of what is happening in the entirehuman body that have never been seen before. PET scanners now give doctors images of only parts of the body.
The U.S. National Institutes of Health gave a research team at the University of California at Davis $15.5 million to build the scanner.
Ramsey Badawi is a professor of radiology at UC Davis. He says the scanner will give researchers new information about how human organs work together.
“We’re a system of organs and all the organs interactwith each other. And we’ve never really been able to interrogatethat with imaging before, and now we’re going to be able to look at that.”
X-raysand MRIsgive images of bones and organs. PET scans show doctors how organs and tissuesare working on a molecular level. These images help them identify and follow diseases. The new scanner will help them do that even better.
Simon Cherry is a professor of biomedical engineering at UC Davis. He says the PET scans can show the progress of both disease and medical treatments.
“With PET scans we’re looking at function. We’re actually able to say something about what the cells in the body are doing -- how actively they’re metabolizing, for example, or how quickly they’re dividing. Taking a cancer example, that could be tremendously powerful to see if, when you give a drug, whether that shuts downthe metabolism of the tumor.”
PET scans use a radioactive substanceto find tumors. Professor Cherry says the Explorer uses a much lower amount of radiation than current PET tests, and creates images more quickly.
“So we can do scans in maybe 30 seconds that currently take 20 minutes. Or we can drop the radiation dosesignificantly, and do scans at a fractionof the radiation dose that we currently do them at.”
A complete view could help researchers develop new medicines that target diseases and parts of the body. It could help doctors reduce harmful side effectsby following the movement of medicines through the body.
The researchers hope to test the Explorer with humans in three years.
I’m Christopher Jones-Cruise.
Words in This Story
device – n.an object, machine or piece of equipment that has been made for some special purpose
scanner – n.a medical device that is used to see inside something
entire – adj.complete or full; not lacking or leaving out any part
interact – v.to act together; to come together and have an effect on each other (often + with)
interrogate– v.to ask questions or research
X-ray – n.an image that is created by using X-rays and that is usually used for medical purposes
MRI – n.magnetic resonance imaging
organs – n.a part of the body (such as the heart or liver) that has a particular function
tissue – n.the material that forms the parts in a plant or animal
function – v.to work or operate
molecular – adj.relating to the smallest possible amount of a particular substance that has all the characteristics of that substance
metabolize – v. to change (food) into a form that can be used by the body; to process and use (substances brought into the body) by metabolism
shut down – expression to stop the operation of something, especially when a special process is required
radioactive – adj.having or producing a powerful and dangerous form of energy (called radiation)
substance – n.a material of a particular kind
tumor – n. a mass of tissue found in or on the body that is made up of abnormal cells
dose – n. the amount of a medicine, drug or vitamin that is taken at one time
fraction – n.a (usually small) part or amount of something
side effect – n.an often harmful and unwanted effect of a drug or chemical that occurs along with the desired effect